Nephritic syndrome epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, Serge Korjian
Overview
Approximately 25% of patients with acute glomerulonephritis present with nephritic syndrome. Acute glomerulonephritis accounts for 10-15% of glomerular diseases in the USA. The reported incidence of glomerulonephritis in adults varies between 0.2 to 2.5/100,000 annually with a male to female ratio reaching 2 to 1. The most common cause of glomerulonephritis worldwide is IgA nephropathy (Berger disease). Approximately 25-30% of patients eventually develop end-stage renal disease (ESRD). The yearly variation of incidence of glomerulonephritis is not validated. While some studies report a decrease in the incidence due to improved healthcare and socioeconomic status, others report an increase in the reported incidence due to increased number of biopsies. Additionally, the true incidence is difficult to predict because the disease might present subclinically.
Epidemiology and Demographics
- Approximately 25% of patients with acute glomerulonephritis present with nephritic syndrome.[1]
- Acute glomerulonephritis accounts for 10-15% of glomerular diseases in the USA.[2]
- The reported incidence of glomerulonephritis in adults varies between 0.2 to 2.5/100,000 annually with a male to female ratio reaching 2 to 1.[3]
- The most common cause of glomerulonephritis worldwide is IgA nephropathy (Berger disease). Approximately 25-30% of patients eventually develop end-stage renal disease (ESRD).[3]
- he yearly variation of incidence of glomerulonephritis is not validated. While some studies report a decrease in the incidence due to improved healthcare and socioeconomic status, others report an increase in the reported incidence due to increased number of biopsies.[3]
- The true incidence is difficult to predict because the disease might present subclinically.
References
- ↑ Chang, A (2009). Glomerulonephritis, Membranopoliferative In: Lang F, ed. Encyclopedia of Molecular Mechanisms of Disease. Springer. pp. 711–6. Unknown parameter
|coauthors=ignored (help) - ↑ Chang, A (2009). Glomerulonephritis, Membranopoliferative In: Lang F, ed. Encyclopedia of Molecular Mechanisms of Disease. Springer. pp. 711–6. Unknown parameter
|coauthors=ignored (help) - ↑ 3.0 3.1 3.2 McGrogan A, Franssen CF, de Vries CS (2011). "The incidence of primary glomerulonephritis worldwide: a systematic review of the literature". Nephrol Dial Transplant. 26 (2): 414–30. doi:10.1093/ndt/gfq665. PMID 21068142.