Nephritic syndrome history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, Serge Korjian

Overview

Symptoms of nephritic syndrome include change in the urine color, decreased urine output, nocturia, and fatigue. In patients with secondary etiologies of glomerular diseases, clinical presentation might be consistent with the etiology of the disease. Patients must always be inquired about recent illnesses, symptoms of vasculitides or other organ involvement, and constitutional symptoms.

Symptoms

• Red urine (or dark urine)
• Headache and blurred vision due to high blood pressure
• Oliguria, defined as low urine output <400 mL/day
• Nocturia
• Edema may or may not be present
• Fatigue and lethargy