Demecarium bromide

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Demecarium is a parasympathomimetic that acts as an acetylcholinesterase inhibitor. It is one of several topical (applied directly to the affected area) medications used to reduce elevated intraocular pressure (IOP) associated with primary glaucoma in cats, dogs, and other animals.^[1]^[2]^[3]

References

↑ Ward D, Abney K, Oliver J (2003). "The effects of topical ocular application of 0.25% demecarium bromide on serum acetylcholinesterase levels in normal dogs". Vet Ophthalmol. 6 (1): 23–5. doi:10.1046/j.1463-5224.2003.00257.x. PMID 12641839.
↑ Krohne S (1994). "Effect of topically applied 2% pilocarpine and 0.25% demecarium bromide on blood-aqueous barrier permeability in dogs". Am J Vet Res. 55 (12): 1729–33. PMID 7887518.
↑ Gum G, Gelatt K, Gelatt J, Jones R (1993). "Effect of topically applied demecarium bromide and echothiophate iodide on intraocular pressure and pupil size in beagles with normotensive eyes and beagles with inherited glaucoma". Am J Vet Res. 54 (2): 287–93. PMID 8430939.

[1] Ward D, Abney K, Oliver J (2003). "The effects of topical ocular application of 0.25% demecarium bromide on serum acetylcholinesterase levels in normal dogs". Vet Ophthalmol. 6 (1): 23–5. doi:10.1046/j.1463-5224.2003.00257.x. PMID 12641839.

[2] Krohne S (1994). "Effect of topically applied 2% pilocarpine and 0.25% demecarium bromide on blood-aqueous barrier permeability in dogs". Am J Vet Res. 55 (12): 1729–33. PMID 7887518.

[3] Gum G, Gelatt K, Gelatt J, Jones R (1993). "Effect of topically applied demecarium bromide and echothiophate iodide on intraocular pressure and pupil size in beagles with normotensive eyes and beagles with inherited glaucoma". Am J Vet Res. 54 (2): 287–93. PMID 8430939.

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Demecarium bromide

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