Hyperhidrosis pathophysiology
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]
Overview
It is not known what causes primary hyperhidrosis. One theory is that hyperhidrosis results from an overactive sympathetic nervous system, but this hyperactivity may in turn be caused by abnormal brain function. Some patients afflicted with the condition experience a certain degree of reduction in their quality of life, depending on how severe their condition is. Sufferers feel at a loss of control because perspiration takes place independent of temperature and emotional state. However, anxiety can exacerbate the situation for many sufferers. A common complaint of patients is that they get nervous because they sweat, then sweat more because they are nervous. Other factors can play a role; certain foods & drinks, nicotine, caffeine, and smells can trigger a response (see also diaphoresis).