Hypesthesia
| Hypesthesia |
Template:Search infobox Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Hypesthesia refers to sensory loss that usually occurs secondary to a problem in the nervous system. Usually coupled with paresthiasis (an abnormal sensation; e.g. tingling or numbness)
Causes
Causes In Alphabetical Order. [1] [2]
- Aura of migraine
- Brainstem lesion
- Cauda equina syndrome
- Cerebral abscess
- Cortical lesion
- Deficiency status
- Inflammatory peripheral neuropathy
- Inherited peripheral neuropathy
- Metabolic peripheral neuropathy
- Mononeuropathy
- Myelopathy
- Paraneoplastic neuropathy
- Plexopathy
- Radiculopathy
- Simple partial seizure
- Subcortical lesions
- Syringomyelia
- Toxic peripheral neuropathy
- Transient ischemic attacks
Diagnosis
History and Symptoms
- Onset (tempo)
- Distribution of paresthesias or hypesthesia
Laboratory Findings
- Complete blood count (CBC)
- Serum protein electrophoresis (SPEP)
- Rheumatoid factor
- Antinuclear antibody
- HIV
- Rapid plasma reagin (RPR)
- Vitamin B12
- Thyroid function tests
- Folate
- Heavy metals
- Hemoglobin A1c
MRI and CT
Other Imaging Findings
Other Diagnostic Studies
- Nerve conduction studies
- Genetic testing
Treatment
- Treat underlying etiologies
- Alleviate offending causes
- Physical therapy
Pharmacotherapy
Acute Pharmacotherapies
- Tricyclic antidepressants
- Anticonvulsants
- Topical preparations
- Epidural injections
- Steroids
- Interferon
- Glatiramer acetate
- Mitoxantrome
Surgery and Device Based Therapy
- Surgical intervention for compressive myelopathies and some cases of radiculopathy