Bronchiectasis natural history, complications and prognosis
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References
Bronchiectasis Natural History, Complications, and Prognosis
- Bronchiectasis has been shown to contribute to early mortality.[1]
- Factors associated with higher mortality were advanced age, poor functional status, more severe disease based on radiographic findings, and evidence of hypoxemia or hypercapnia.
- In US long-term cohort of 91 patients, 30% died during a 13-year follow-up period (median age 60 years).[1]
- Early mortality was associated with male sex.[1]
- Bronchiectasis related to Pseudomonas aeruginosa, severe exacerbations, systemic inflammation are associated with disease progression
- 10% of adults with bronchiectasis die within 5-8 years of diagnosis, majority with the cause of death being respiratory related
- Good nutrition,ideal body weight, and regular vaccinations correlate with improved survival
- ↑ 1.0 1.1 1.2 McDonnell MJ, Ward C, Lordan JL, Rutherford RM (2013). "Non-cystic fibrosis bronchiectasis". QJM. 106 (8): 709–15. doi:10.1093/qjmed/hct109. PMID 23728208.