Dermatofibroma pathophysiology
|
Dermatofibroma Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Dermatofibroma pathophysiology On the Web |
|
American Roentgen Ray Society Images of Dermatofibroma pathophysiology |
|
Risk calculators and risk factors for Dermatofibroma pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Shivali Marketkar, M.B.B.S. [2], Faizan Sheraz, M.D. [3]
Overview
Dermatofibromas are composed of disordered collagen laid down by fibroblasts.
Pathophysiology
Dermatofibromas form as a reaction to previous injuries such as insect bites or thorn pricks. Dermatofibromas are composed of disordered collagen laid down by fibroblasts.
Immunohistochemical staining
| Neoplasm | CD34 | Stromelysin-3[1] | Factor XIIIa[2] |
|---|---|---|---|
| Dermatofibroma | + | + | + |
| Dermatofibrosarcoma protuberans | + | - | - |
Video
{{#ev:youtube|tq4xFLIw1TA}}
References
- ↑ Kim HJ, Lee JY, Kim SH; et al. (2007). "Stromelysin-3 expression in the differential diagnosis of dermatofibroma and dermatofibrosarcoma protuberans: comparison with factor XIIIa and CD34". Br. J. Dermatol. 157 (2): 319–24. doi:10.1111/j.1365-2133.2007.08033.x. PMID 17596171. Unknown parameter
|month=ignored (help) - ↑ http://emedicine.medscape.com/article/1056742-overview