Gallbladder cancer risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Risk factors
- Obesity increases the risk for gallbladder cancer
- Chronic cholecystitis and cholelithiasis
- Chronic typhoid infection of gallbladder. Chronic salmonella typhi carriers have 3 to 200 times higher risk of gallbladder cancer than non-carriers and 1–6% lifetime risk of development of cancer[1]
- Various single nucleotide polymorphisms (SNPs) have been shown to be associated with gallbladder cancer. However, existing genetic studies in GBC susceptibility have so far been insufficient to confirm any association[2]
- Alcohol: Alcohol drinking is a risk factor of gallbladder canc"[3] [4]
References
- ↑ Template:Cite doi
- ↑ Srivastava K, Srivastava A, Sharma KL, Mittal B. Candidate gene studies in gallbladder cancer: a systematic review and meta-analysis. Mutat Res. 2011 Jul-Oct;728(1-2):67-79.
- ↑ Ji, J (2005 Sep). "Variation in the risk for liver and gallbladder cancers in socioeconomic and occupational groups in Sweden with etiological implications". Int Arch Occup Environ Health. 78 (8): 641–9. PMID 16001211. Retrieved 28 May 2007. Unknown parameter
|coauthors=ignored (help); Check date values in:|date=(help) - ↑ Ji J, Couto E, Hemminki K. Incidence differences for gallbladder cancer between occupational groups suggest an etiological role for alcohol Int J Cancer 2005 Sep 1;116(3):492-3.