Glomus tumor natural history
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
Prognosis
The most common adverse effect is pain, which is usually associated with solitary lesions. Multiple tumors are less likely to be painful. In one report, a patient with more than 400 glomus tumors had thrombocytopenia as a result of platelet sequestration (ie, Kasabach-Merritt syndrome). Malignant glomus tumors, or glomangiosarcomas, are extremely rare and usually represent a locally infiltrative malignancy. However, metastases do occur and are usually fatal.
Patients who have surgery or radiation tend to do well.
Complications
- nail deformity, recurrence is a possible complication and may occur in up to 20% of cases.2 Recurrence is thought to be a result of incomplete excision or, in the case of late recurrence, development of a new lesion at or near the excision site. Excision of the capsule of the tumor is required to prevent local recurrence.[1]