Diffuse large B cell lymphoma laboratory tests
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Laboratory tests helpful in the diagnosis of diffuse large B cell lymphoma include complete blood count, LDH, and lymph node biopsy
Laboratory Tests
Laboratory studies include[1]
- Complete blood count
- Serum lactate dehydrogenase (LDH)
- Comprehensive metabolic panel
- Immunohistological panel
- Essential: CD3, CD5, CD10, CD20, BCL2, BCL6, and IRF4/MUM1
- May be additionally required: Ki-67, CD43, CD21, and CD23
- Pregnancy test among female patients who are planned to undergo chemotherapy
- Hepatitis B testing prior to initiation of treatment among patients who either receive anti-CD20 monoclonal antibody-based regimens or patients with at least one risk factor
- Hepatitis C among high-risk patients