Gallbladder cancer laboratory tests

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

There are no diagnostic laboratory findings associated with gallbladder cancer

Laboratory tests

• Laboratory studies are usually nondiagnostic;
• An elevated alkaline phosphatase or serum bilirubin can be associated with bile duct obstruction.
• Serum tumor markers including carcinoembryonic antigen (CEA) or carbohydrate antigen 19-9 are frequently elevated, but they're no longer diagnostically useful because they lack specificity and sensitivity.
• CA 242 is a tumor marker for gallbladder cancer and performs better than CEA and CA 19-9
• However, if a tumor marker is observed to be elevated preoperatively, serial assay after resection may useful resource within the analysis of chronic or recurrent disease.