Adrenocortical carcinoma natural history
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Adrenocortical carcinoma Microchapters |
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Differentiating Adrenocortical carcinoma from other Diseases |
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Diagnosis |
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Treatment |
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Case Study |
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Adrenocortical carcinoma natural history On the Web |
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American Roentgen Ray Society Images of Adrenocortical carcinoma natural history |
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Risk calculators and risk factors for Adrenocortical carcinoma natural history |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2] Ahmad Al Maradni, M.D. [3]
Complications
The following are the complications of Adrenocortical carcinoma:
- Cushing's syndrome
- Conn syndrome
- Hypertension
- Virilization
- Feminization
- Local metastasis and tumor thrombus formation
- Paraneoplastic syndrome
- Distant metastasis
Prognosis
Adrenocortical carcinoma, generally, carries a poor prognosis.[1] Five-year disease-free survival for a complete resection of a stage I-III is approximately 30%.[1] The most important prognostic factors are:
- Age of the patient.
- Stage of the tumor.
Poor prognostic factors include:
- Mitotic activity.
- Venous invasion.
- Weight more than 50 Kg.
- Diameter more than 6.5 cm.
- Ki-67/MIB1 labeling index.
References
- ↑ 1.0 1.1 Allolio B, Fassnacht M (2006). "Clinical review: Adrenocortical carcinoma: clinical update". J Clin Endocrinol Metab. 91 (6): 2027–37. PMID 16551738. Free Full Text.