Adrenocortical carcinoma risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]

Overview

The most potent risk factors in the development of adrenocortical cancer are TP53 mutation, Beckwith-Wiedemann syndrome and Carney complex.

Common Risk Factors

Families with Li-Fraumeni syndrome (TP53 mutation), Beckwith-Wiedemann syndrome and Carney complex have increased risk for adrenocortical cancer.