Acute lymphoblastic leukemia epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]; Rim Halaby, M.D. [3] Carlos A Lopez, M.D. [4]
Overview
In 2011, the incidence of acute lymphocytic leukemia was estimated to be 1.77 cases per 100,000 individuals and the prevalence of 17.4 per 100,000 individuals in the United States. In 2015 according with the National cancer institute the incidence of acute lymphocytic leukemia is 1.9 per 100,000 individuals and the mortality rate of .45 per 100,000 individuals in the United States. The incidence of acute lymphoblastic leukemia is estimated to be roughly 4000, 3000 of which inflict children cases per year. Acute lymphoblastic leukemia is slightly more common to affect males than females. Males are more commonly affected with 19.3 per 100,000 than females with 15.4 per 100,000 individuals. Acute lymphoblastic leukemia accounts for approximately 80 percent of all childhood leukemia cases, making it the most common type of childhood cancer.
In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide. The prevalence of [disease/malignancy] is estimated to be [number] cases annually. [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2]. [Gender 1] are more commonly affected with [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.
American Cancer Society estimated in 2015 that new cases and deaths from Acute lymphocytic leukemia in the United States will be 6,250 and 1,450 respectively. The age-adjusted prevalence of acute lymphoblastic leukemia is 17.4 per 100,000 in 2011.[1] There is an increased incidence in people with Down's Syndrome, Fanconi's anemia, Bloom's syndrome, ataxia-telangiectasia, X-linked agammaglobulinemia and severe combined immunodeficiency. ALL accounts for approximately 80 percent of all childhood leukemia cases, making it the most common type of childhood cancer.
Epidemiology and Demographics
Incidence and Mortality 2015
- Estimated new cases and deaths from Acute lymphoblastic leukemia in the United States in 2015[2]
- Incidence: 1.9%
- Fatality rate: .45%
Prevalence
- In the United States, the age-adjusted prevalence of Acute lymphoblastic leukemia is 17.4 per 100,000 in 2011.[1]
Incidence
- The number of annual acute lymphoblastic leukemia cases in the United States is roughly 4000, 3000 of which inflict children.
- There is an increased incidence in people with Down's Syndrome, Fanconi's anemia, Bloom's syndrome, ataxia-telangiectasia, X-linked agammaglobulinemia and severe combined immunodeficiency.
- In 2011, the age-adjusted incidence of Acute lymphoblastic leukemia was 1.77 per 100,000 persons in the United States.[1]
Age
- Acute lymphoblastic leukemia accounts for approximately 80 percent of all childhood leukemia cases, making it the most common type of childhood cancer.
- It has a peak incident rate of 2-5 years old, decreasing in incidence with increasing age before increasing again at around 50 years old.
- While the overall age-adjusted incidence of Acute lymphoblastic leukemia in the United States between 2007 and 2011 is 1.7 per 100,000, the age-adjusted incidence of Acute lymphoblastic leukemia by age category is:[1]
- Under 65 years: 1.7 per 100,000
- 65 and over: 1.6 per 100,000
Gender
- Acute lymphoblastic leukemia is slightly more common in males than females.
- In the United States, the age-adjusted prevalence of Acute lymphoblastic leukemia by gender in 2011 is:[1]
- In males: 19.3 per 100,000
- In females: 15.4 per 100,000
- In the United States, the age-adjusted incidence of Acute lymphoblastic leukemia by gender on 2011 is:[1]
- In males: 1.9 per 100,000 persons
- In females: 1.63 per 100,000 persons
- Shown below is an image depicting the observed incidence of lymphocytic leukemia by gender in the United States between 1975 and 2011. These graphs are adapted from SEER: The Surveillance, Epidemiology, and End Results Program of the National Cancer Institute.[1]
Race
- Shown below is a table depicting the age-adjusted prevalence of Acute lymphoblastic leukemia by race in 2011 in the United States.[1]
| All Races | White | Black | Asian/Pacific Islander | Hispanic | |
| Age-adjusted prevalence | 17.4 per 100,000 | 20 per 100,000 | 7.6 per 100,000 | 13.2 per 100,000 | 20.8 per 100,000 |
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.
- ↑ "National Cancer Institurte".