Adrenocortical carcinoma classification
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Differentiating Adrenocortical carcinoma from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2] Ahmad Al Maradni, M.D. [3]
Overview
Adrenocortical carcinoma is classified according to hormone production and histological appearance. ACC may secrete Cortisol, Aldosterone, Testosterone, Estrogen. Other variants include oncocytic adrenal cortical carcinoma, myxoid adrenal cortical carcinoma, and carcinosarcoma.
Classification
Adrenocortical carcinomas are classified depending on:
Hormones production
- Functional, produce one or more of the followings hormones:
- Cortisol
- Aldosterone
- Testosterone
- Estrogen
- Nonfunctional
Histology
- Well differentiated
- Intermediate differentiated
- Poorly differentiated
- Anaplastic
Variants
- Oncocytic adrenal cortical carcinoma
- Myxoid adrenal cortical carcinoma
- Carcinosarcoma
- Adenosquamous adrenocortical carcinoma
- Clear cell adrenal cortical carcinoma