Stomach cancer endoscopy and biopsy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Biopsy may be helpful in the diagnosis of stomach cancer.

A single biopsy has a 70 percent sensitivity for diagnosing an existing gastric cancer while performing seven biopsies from the ulcer margin and base increases the sensitivity to greater than 98 percent [14].

Superficial mucosal biopsies may be falsely negative as in linitis plastica cancers. So, the combination of strip and bite biopsy techniques should be used when there is a suspicion of a diffuse type of gastric cancer [15].