Ganglioglioma MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

On MRI brain, ganglioglioma is characterized by iso- to hypointense solid component on T1, variable contrast enhancement of solid component on T1 C+ (Gd), hyperintense solid component and variable signal in cystic component on T2, and calcification on T2 (GE/SWI).[1] On MRI scan of spinal cord, ganglioglioma is characterized by mixed signal intensity on T1-weighted images, high intensity on T2, patchy enhancement on T1 C+ (Gd), and calcification with low signal blooming on gradient echo.[2]

MRI

  • 1. Brain MRI scan is helpful in the diagnosis of cerebral ganglioglioma. On MRI brain, it is characterized by:[1]
Number MRI Component Findings
1 T1 Solid component iso- to hypointense
2 T1 C+ (Gd) Solid component variable contrast enhancement
3 T2 Hyperintense solid component
Variable signal in the cystic component
peritumoral flair/T2 edema is rare
4 T2 (GE/SWI) Calcified areas shows blooming signal loss
  • 2. MRI scan of spinal cord is helpful in the diagnosis of spinal cord ganglioglioma. On MRI scan of spinal cord, it is characterized by:[2]
' MRI Component Findings
1 T1 Mixed signal intensity
2 T1 C+ (Gd) Patchy enhancement
3 T2 High intensity
Surrounding edema is rare
4 Gradient echo Calcification is common, low signal with blooming

References

  1. 1.0 1.1 MRI findings of ganglioglioma. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/ganglioglioma
  2. 2.0 2.1 MRI findings of spinal cord ganglioglioma. Dr Ayush Goel and Dr Sara Wein et al. Radiopaedia 2015. http://radiopaedia.org/articles/spinal-ganglioglioma


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