Multiple myeloma x ray
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
On X-ray radiography, multiple myeloma is characterized by punched out bony lesions, generalized osteopaenia, and hair on end appearance.
X Ray
- Simple radiography is the current gold standard for the initial diagnosis and evaluation of relapses of multiple myeloma. The long bones and the spine must always be evaluated while the evaluation of other bones merit consideration based on the symptoms of the patient.[1]
- A plain film skeletal survey is essential in not only the diagnosis of multiple myeloma, but also in assessing response, and pre-empting potential complications (e.g. pathological fracture). A typical skeletal survey consists of the following films:[2]
- lateral skull
- frontal chest film
- cervico-thoraco-lumbar spine
- shoulders
- pelvis
- femurs
- The vast majority of lesions seen on plain radiography are purely lytic, sharply defined/punched out with endosteal scalloping when abutting cortex. In only 3% of patients are the lesions sclerotic.[3]
- Shown below are images depicting, the involvement of skull and spinal cord respectively in a case of multiple myeloma.
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X ray showing hair on end appearance.
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X ray spine showing collapsed vertebrae.
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X ray spine showing increased space between 2 vertebrae suggestive of possible malignancy.
References
- ↑ Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015
- ↑ Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015
- ↑ Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015