Meningioma natural history
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Risk calculators and risk factors for Meningioma natural history |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
If left untreated, patients with meningioma may progress to develop morning headache, focal neurological deficit, and altered mental status. Common complications of meningioma include increased intracranial pressure, cranial nerve palsy, and hydrocephalus. Prognosis is generally good, and the survival rate of patients with meningioma mainly depends on the grade and location of the tumor.
Natural History
Complications
Prognosis
- Depending on the histological grade of the meningioma at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as good.[1]
- The table below lists common prognostic factors for meningioma:[2]
| Prognostic Factor | Description |
| Age | Older patients are associated with a worse prognosis.[2] |
| Anatomical location | Deep tumor location is associated with difficult surgical resection.[2] |
| Labeling index using MIB-1 test | A greater index is associated with a worse prognosis.[2] |
| Histological grade | A grade 3 anaplastic meningioma is associated with the worst prognosis.[2] |
| Functional neurological status | Low score on the Karnofsky Performance Scale is associated with a worse prognosis.[2] |
References
- ↑ Meningioma. Wikipedia(2015) https://en.wikipedia.org/wiki/Meningioma#cite_ref-17 Accessed on September, 25th 2015
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Meningioma: Stages and Grades Cancer.net(2015) http://www.cancer.net/cancer-types/meningioma/stages-and-grades Accessed on September, 25th 2015