Burkitt's lymphoma medical therapy

Revision as of 20:20, 28 September 2015 by Sowminya Arikapudi (talk | contribs)
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Overview

The predominant therapy for Burkitt's lymphoma is chemotherapy. Adjunctive immunotherapy and stem cell transplantation may be required.

Medical Therapy

Chemotherapy

Biological therapy

  • Monoclonal antibodies are a type of biological therapy that is effective in treating Burkitt's lymphoma
  • Rituximab may be added to each of the above chemotherapy regimens

CNS prophylaxis

  • There is a high risk that Burkitt's lymphoma will spread to the central nervous system (CNS)
  • CNS prophylaxis may involve giving intrathecal chemotherapy high doses of systemic therapy, or both methods may be used
  • Methotrexate and Cytarabine are the drugs used most often for CNS prophylaxis

Stem cell transplant

  • A Stem cell transplant may be offered to some people with Burkitt's lymphoma if their lymphoma returns or relapses after treatment

References

Template:Chromosomal abnormalities


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