Medulloblastoma epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Epidemiology and Demographics
Prevalance
Incidence
- The overall age adjusted incidence rate of medulloblastoma is approximately 0.71 per 100,000 individuals in the United States.[1]
Age
- Medulloblastoma is the second most common brain tumor among the pediatric population, as it comprise 14.5% of newly diagnosed cases.[2]
- Medulloblastoma is considered a rare tumor among adults , as it compromise fewer than 2% of all brain tumors.
- The molecular subtgroup of medulloblastoma influence the age of presentation such as:[3]
- WNT medulloblastoma subgroup present among older children
- SHH medulloblastoma subgroup present among infants and adults
- Group 3 medulloblastoma present among younger children
- Group 4 medulloblastoma present among younger younger children
Gender
- The overall age adjusted incidence rate of medulloblastoma among male patients is approximately 0.84 per 100,000 individuals in the United States.[1]
- The overall age adjusted incidence rate of medulloblastoma among female patients is approximately 0.58 per 100,000 individuals in the United States.
- Males are more commonly affected with medulloblastoma than females. The male to female ratio is approximately 1.44 to 1.
Race
References
- ↑ 1.0 1.1 McKean-Cowdin R, Razavi P, Barrington-Trimis J, Baldwin RT, Asgharzadeh S, Cockburn M; et al. (2013). "Trends in childhood brain tumor incidence, 1973-2009". J Neurooncol. 115 (2): 153–60. doi:10.1007/s11060-013-1212-5. PMC 4056769. PMID 23925828.
- ↑ Medulloblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Medulloblastoma Accessed on September, 28th 2015
- ↑ Leary SE, Olson JM (2012) The molecular classification of medulloblastoma: driving the next generation clinical trials. Curr Opin Pediatr 24 (1):33-9. DOI:10.1097/MOP.0b013e32834ec106 PMID: 22189395