B-cell prolymphocytic leukemia
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B-cell prolymphocytic leukemia |
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Differentiating B-cell prolymphocytic leukemia from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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B-cell prolymphocytic leukemia On the Web |
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American Roentgen Ray Society Images of B-cell prolymphocytic leukemia |
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Directions to Hospitals Treating B-cell prolymphocytic leukemia |
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Risk calculators and risk factors for B-cell prolymphocytic leukemia |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Carlos A Lopez, M.D. [2]
Synonyms and keywords: B-PLL
Overview
Historical Perspective
Classification
Pathophysiology
Differentiating B-cell prolymphocytic leukemia from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | CT | MRI | Other Imaging Findings | Other Diagnostic Studies
Treatment
Medical Therapy | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies
Overview
B-cell prolymphocytic leukemia is a more aggressive but still treatable form of leukemia. The malignant B cells are larger than average.
Diagnosis exam
- Blood chemistry studies
- Bone marrow aspiration and biopsy
- Complete blood count (CBC)
- CT (CAT) scan
- Cytogenetic analysis
- Immunophenotyping
- Peripheral blood smear
- Physical exam and history (H&P)
Stem cell trasplant
A stem cell transplant is sometimes used to treat people with aggressive prolymphocytic leukemia. Many people with prolymphocytic leukemia are older or may not be in good health, so a stem cell trasplant is often not a suitable option for them. However, it may be an effective option for younger people with prolymphocytic leukemia.