Optic nerve glioma epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
There is no racial predilection to the optic nerve glioma.[1] Optic nerve gliomas affects females and males equally.
Epidemiology and Demographics
Optic nerve gliomas typically present in children, and often in the setting of NF1 (10-63%). In adults, optic nerve gliomas do occur but are very rare and usually aggressive tumors. In such cases no association with NF1 has been found.[2] 5 % of all childhood brain tumors account for optic nerve gliomas. About 1% of all intracranial tumors are comprised of optic-nerve gliomas.[3] It is most common in children who have the genetic condition neurofibromatosis 1 (NF1).
Incidence
The incidence of NF-1 among patients of optic nerve glioma is 10-70% and the incidence of optic nerve glioma in patients with NF-1 varies from 8 to 31 %.[4]
Gender
Males and females are equally affected.
Age
The mean age of presentation of optic nerve glioma is 8.8 years.[5] Most optic gliomas occur in children, are slow-growing and noncancerous and almost always occur before age 20.[2]
| Age of onset of optic nerve glioma | Percentage of optic nerve glioma diagnosed |
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25% |
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50% |
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75% |
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90% |
Race
There are no racial or ethnic groups that are at more risk than others of optic nerve gliomas.
References
- ↑ Optic nerve glioma. Radiopedia(2015) http://radiopaedia.org/articles/optic-nerve-glioma Accessed on October 2 2015
- ↑ 2.0 2.1 Optic glioma. Medline Plus(2015) https://www.nlm.nih.gov/medlineplus/ency/article/001024.htm Accessed on October 5 2015
- ↑ Dutton JJ (1994). "Gliomas of the anterior visual pathway". Surv Ophthalmol. 38 (5): 427–52. PMID 8009427.
- ↑ Nair AG, Pathak RS, Iyer VR, Gandhi RA (2014). [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?
dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24736941 "Optic nerve glioma: an update"] Check
|url=value (help). Int Ophthalmol. 34 (4): 999–1005. doi:10.1007/s10792-014-9942-8. PMID 24736941. line feed character in|url=at position 54 (help) - ↑ Alvord EC, Lofton S (1988). "Gliomas of the optic nerve or chiasm. Outcome by patients' age, tumor site, and treatment". J Neurosurg. 68 (1): 85–98. doi:10.3171/jns.1988.68.1.0085. PMID 3275755.