Oligodendroglioma surgery

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Surgery is the first-line treatment option for patients with oligodendroglioma.^[1] CSF shunting is usually reserved for patients with hydrocephalus.^[2]

Surgery

Surgical Resection

Surgery is the first-line treatment option for patients with oligodendroglioma.^[1]
Because of their diffusely infiltrating nature, oligodendrogliomas cannot be completely resected and are not curable by surgical excision.
The aim of surgery is to:^[3]
- Make a definitive diagnosis
- Debulk the tumor to relieve elevated intracranial pressure
- Reduce the tumor mass as a precursor to adjuvant treatment

CSF Shunt

CSF shunting is performed to relieve the pressure in the brain due to blockade in the flow of cerebrospinal fluid due to oligodendroglioma.^[2]
- External ventricular drain
  - Temporary shunt
- Internal drain
  - Permanent shunt
  - Drains CSF into the patient’s abdomen, where it is absorbed into the body

References

↑ ^1.0 ^1.1 Treatment of oligodendroglioma. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/brain-spinal/brain-and-spinal-tumours/oligodendroglioma/?region=on
↑ ^2.0 ^2.1 Stark AM, Hugo HH, Mehdorn HM, Knerlich-Lukoschus F (2009). "Acute Hydrocephalus due to Secondary Leptomeningeal Dissemination of an Anaplastic Oligodendroglioma". Case Rep Med. 2009: 370901. doi:10.1155/2009/370901. PMC 2797365. PMID 20052406.
↑ Eskandar EN, Loeffler JS, O'Neill AM, Hunter GJ, Louis DN (2004). "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2004. A 34-year-old man with a seizure and a frontal-lobe brain lesion". N Engl J Med. 351 (18): 1875–82. doi:10.1056/NEJMcpc049025. PMID 15509821.

Template:WikiDoc Sources

[rx-1] 1.0 ^1.1 Treatment of oligodendroglioma. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/brain-spinal/brain-and-spinal-tumours/oligodendroglioma/?region=on

[pmid20052406-2] 2.0 ^2.1 Stark AM, Hugo HH, Mehdorn HM, Knerlich-Lukoschus F (2009). "Acute Hydrocephalus due to Secondary Leptomeningeal Dissemination of an Anaplastic Oligodendroglioma". Case Rep Med. 2009: 370901. doi:10.1155/2009/370901. PMC 2797365. PMID 20052406.

[pmid15509821-3] Eskandar EN, Loeffler JS, O'Neill AM, Hunter GJ, Louis DN (2004). "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2004. A 34-year-old man with a seizure and a frontal-lobe brain lesion". N Engl J Med. 351 (18): 1875–82. doi:10.1056/NEJMcpc049025. PMID 15509821.

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