Myeloproliferative neoplasm classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
Myeloproliferative disease may be classified according to the World Health Organization into eight subtypes: chronic myelogenous leukemia, chronic neutrophilic leukemia, polycythemia vera, primary myelofibrosis, essential thrombocythemia, chronic eosinophilic leukemia, mastocytosis, and myeloproliferative neoplasms, unclassifiable.
Classification
WHO Classification of Myeloproliferative Neoplasms (MPN)
- Chronic myelogenous leukemia, BCR-ABL1–positive
- Chronic neutrophilic leukemia
- Polycythemia vera
- Primary myelofibrosis
- Essential thrombocythemia
- Chronic eosinophilic leukemia, not otherwise specified
- Mastocytosis
- – Cutaneous mastocytosis
- – Systemic mastocytosis
- – Mast cell leukemia
- – Mast cell sarcoma
- – Extracutaneous mastocytoma
- Myeloproliferative neoplasms, unclassifiable[1]
References
- ↑ Vardiman, James W.; Thiele, Jüergen; Arber, Daniel A.; Brunning, Richard D.; Borowitz, Michael J.; Porwit, Anna; Harris, Nancy Lee; Le Beau, Michelle M.; Hellström-Lindberg, Eva; Tefferi, Ayalew; Bloomfield, Clara D. (2009-07-30). "The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes". Blood. 114 (5): 937–951. doi:10.1182/blood-2009-03-209262. ISSN 1528-0020. PMID 19357394.