Brain abscess differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Brain abscess must be differentiated from metastatic tumors and necrotic tumors.[1]

Differential Diagnosis

  • Some studies suggest that indium scans can help differentiate abscess from CA, and thallium SPECT scans can distinguish CNS toxoplasmosis from lymphoma.[2]
  • The big differential is metastatic tumor: abscesses are often located in watershed regions, and tumors often enhance diffusely with contrast.
  • Diagnosis of brain abscesses and necrotic tumors is often impossible without conventional MR imaging.[1]

Despite these differences, the true diagnosis is sometimes not made until biopsy.

References

  1. 1.0 1.1 Desprechins B, Stadnik T, Koerts G, Shabana W, Breucq C, Osteaux M (1999). "Use of diffusion-weighted MR imaging in differential diagnosis between intracerebral necrotic tumors and cerebral abscesses". AJNR Am J Neuroradiol. 20 (7): 1252–7. PMID 10472982.
  2. Ruiz A, Ganz WI, Post MJ, Camp A, Landy H, Mallin W; et al. (1994). "Use of thallium-201 brain SPECT to differentiate cerebral lymphoma from toxoplasma encephalitis in AIDS patients". AJNR Am J Neuroradiol. 15 (10): 1885–94. PMID 7863938.

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