Essential thrombocytosis history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Patients with a mild form of disease are usually asymptomatic. Most of the symptoms are vascular, either from thrombii occluding small and large blood vessels, though any blood vessel may be involved. Symptoms depend on the blood vessel occluded and include but are not limited to the following:

  • Headache, dizziness
  • Vision disturbances
  • Chest pain
  • Intense burning pain in hands or feet(erythromelalgia)
  • Numbness and tingling of hands and feet



Although less common, bleeding can occur despite the increased platelet count accounting to the dysfunctional platelets.

and to  symptoms are bleeding and thrombosis.  Other symptoms include epistaxis (nosebleeds) and bleeding from gums and gastrointestinal tract.  One characteristic symptom is throbbing and burning of the hands and feet due to the occlusion of small arterioles by platelets (erythromelalgia).

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