Sandbox: DDx Kidney mass

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  • Detected prenatally
  • Bilateral kidney involvement results in stillbirth
  • Irregular, mobile, nontender, flank abdominal mass in infants
  • Lobulated renal contour
  • Multiple, noncommunicating cysts
  • Cluster of cysts with variable sizes (1mm-2cm) and shapes
  • Dysplastic parenchyma
  • Absence of a normal pelvocaliceal system


  • Nests of metaplastic cartilage and undifferentiated epithelial ducts
  • Extensive fibrous tissue stroma
  • Thin-walled cysts cysts filled with yellow/clear fluid











Nonmalignant causes

glomerulocystic kidney  mesothelial cysts nephronophthisis