Gestational trophoblastic neoplasia history and symptoms

Gestational trophoblastic neoplasia Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]

Overview

Symptoms of choriocarcinoma include vaginal bleeding, passing of tissue resembling a “bunch of grapes” from the vagina, and abdominal distention.

History

The medical history is a record of present symptoms, risk factors, all the medical events, and problems a person has had in the past. The patients family history is also required. The specific questions regarding patients history include:

• History of previous pregnancies, including hydatidiform mole (molar pregnancy) and miscarriage
• History of previous GTD
• Reproductive factors that may increase the risk of gestational trophoblastic disease (GTD)
• A family history of gestational trophoblastic disease (GTD)
• Signs and symptoms that may suggest gestational trophoblastic disease (GTD)

Symptoms

Early symptoms of gestational trophoblastic disease

• Vaginal bleeding
• Nausea and vomiting
• Passing of tissue resembling a “bunch of grapes” from the vagina
• Absent fetal movement during pregnancy
• Abdominal distention

Rare symptoms of gestational trophoblastic disease

• Headache
• Edema of the hands and feet
• Abdominal or pelvic pain
• Vaginal discharge
• Overactive thyroid gland (hyperthyroidism) that causes:

• Tachycardia
• Sweating
• Shaking
• Heat intolerance
• Fever

Late symptoms gestational trophoblastic disease

• Hemoptysis
• Dry cough
• Chest pain
• Trouble breathing
• Headache
• Dizziness
• Jaundice
• Paralysis
• Seizure
• Dysarthria and dysphasia
• Vision problems
• Lump in the vagina