Hepatic hemangioma pathophysiology
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Hepatic hemangioma pathophysiology On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
They arise from the endothelial cells that line the blood vessels and consists of multiple, large vascular channels lined by a single layer of endothelial cells and supported by collagenous walls.
Pathophysiology
Pathogenesis
- They arise from the endothelial cells that line the blood vessels and consists of multiple, large vascular channels lined by a single layer of endothelial cells and supported by collagenous walls.
- They may be associated with focal nodular hyperplasia.
Associated Conditions
May be associated with:
- Kasabach-Merritt syndrome
- Hemolytic anemia
- Consumptive coagulopathy
Gross Pathology
On gross pathology, variable in size, well circumscribed, classically subcapsular are characteristic findings of hepatic hemangioma.[1]
Microscopic Pathology
On microscopic histopathological analysis channels lined by benign endothelium containing RBCs, surrounding (non-endothelial) cells without significant atypia are characteristic findings of hepatic hemangioma.[1]
Gallery
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Intermediate magnification micrograph of a cavernous hemangioma of the liver, also hepatic cavernous hemangioma, liver hemangioma,cavernous liver hemangioma. H&E stain. No liver tissue is observed.
References
- ↑ 1.0 1.1 Gross pathology of hepatic hemangioma. Librepathology 2015. http://librepathology.org/wiki/index.php/Hemangioma_of_the_liver. Accessed on October 20, 2015
- ↑ Image of microscopy of Hepatic hemangioma. Librepathology 2015. http://librepathology.org/wiki/index.php/Hemangioma_of_the_liver. Accessed on October 20, 2015