Metanephric adenoma pathophysiology
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]
Overview
On gross pathology, a sharply circumscribed, nonencapsulated solitary mass is the characteristic finding of metanephric adenoma. On microscopic histopathological analysis, small uniform cells with fine chromatin and smooth nuclear membrane, variable architecture, and psammoma bodies are characteristic findings of metanephric adenoma.
Gross Pathology
Characteristic findings of metanephric adenoma on gross pathology include:[1]
- Solitary mass
- Sharply circumscribed
- Not encapsulated
Microscopic Pathology
The characteristics of metanephric adenomas include:[2]
- Small uniform cells with:
- Fine chromatin
- No apparent nucleolus
- Smooth nuclear membrane
- Variable architecture:
- May be sheets, ductal or micropapillary
- Psammoma bodies may present
-
Metanephric adenoma[3]
Genetics
References
- ↑ Metanephric adenoma. Libre Pathology 2015. http://librepathology.org/wiki/index.php/Metanephric_adenoma Accessed on November 9, 2015
- ↑ Metanephric adenoma. Libre Pathology 2015. http://librepathology.org/wiki/index.php/Metanephric_adenoma Accessed on November 9, 2015
- ↑ Metanephric adenoma. Libre Pathology 2015. http://librepathology.org/wiki/index.php/Metanephric_adenoma Accessed on November 9, 2015