Intracerebral metastases medical therapy
Intracerebral metastases Microchapters |
Differentiating Intracerebral Metastases from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Medical Therapy
Symptomatic Treatment
- Corticosteroids are given to limit the effects of peritumoral edema.[1]
- Hyperosmolar agents (i.e., mannitol) can be given to reduce intracranial pressure
- Anticonvulsants are given to prevent seizures.
- Recently, methylphenidate and donepezil have been used to improve cognition, mood, and quality of life.
Therapeutic
Radiation Therapy
- The most widely used treatment for patients with multiple brain metastases is whole brain external beam radiotherapy (WBRT).[1]
- Stereotactic radiosurgery is done for smaller masses.