Ovarian germ cell tumor medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]

Overview

The mainstay of therapy for ovarian germ cell tumor is chemotherapy.^[1]^[2]^[3]^[4]

The mainstay of therapy for ovarian germ cell tumor is chemotherapy.^[5]^[6]^[7]^[8]

Standard treatment options:
Dysgerminomas
Unilateral salpingo-oophorectomy with adjuvant radiation therapy or chemotherapy
Other germ cell tumors
Unilateral salpingo-oophorectomy with adjuvant chemotherapy

Standard treatment options:
Dysgerminomas
Total abdominal hysterectomy and bilateral salpingo-oophorectomy with adjuvant radiation therapy or chemotherapy
Unilateral salpingo-oophorectomy with adjuvant chemotherapy
Other germ cell tumors
Unilateral salpingo-oophorectomy with adjuvant chemotherapy

Standard treatment options:
Dysgerminomas
Unilateral salpingo-oophorectomy with adjuvant chemotherapy
Other germ cell tumors
Total abdominal hysterectomy and bilateral salpingo-oophorectomy with adjuvant chemotherapy, with or without neoadjuvant chemotherapy
Unilateral salpingo-oophorectomy with adjuvant chemotherapy, with or without neoadjuvant chemotherapy

Standard treatment options:
Dysgerminomas
Total abdominal hysterectomy and bilateral salpingo-oophorectomy with adjuvant chemotherapy
Unilateral salpingo-oophorectomy with adjuvant chemotherapy
Other germ cell tumors
Total abdominal hysterectomy and bilateral salpingo-oophorectomy with adjuvant chemotherapy with or without neoadjuvant chemotherapy
Unilateral salpingo-oophorectomy with adjuvant chemotherapy with or without neoadjuvant chemotherapy