Medullary thyroid cancer historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Medullary thyroid cancer was first discovered by John Beach Hazard, an American pathologist, in 1959 following a specimen he observed which had solid non-follicular structure with amyloid in the stroma.[1]
Historical Perspective
- In 1959 Hazard et al. described medullary (solid) thyroid carcinoma.[2]
- In 1961 Sipple described a combination of a pheochromocytoma, medullary thyroid carcinoma and parathyroid adenoma.
- In 1966 Williams et al. described the combination of mucosal neuromas, pheochromocytoma and medullary thyroid carcinoma.
- In 1978, Cameron suggested that medullary thyroid cancer produces thyrocalcitonin from parafollicular cells.
Discovery
Medullary thyroid cancer was first discovered by John Beach Hazard, an American pathologist, in 1959 following a specimen he observed which had solid non-follicular structure with amyloid in the stroma.[1]
Landmark Events in the Development of Treatment Strategies
Impact on Cultural History
Famous Cases
References
- ↑ 1.0 1.1 HAZARD JB, HAWK WA, CRILE G (1959). "Medullary (solid) carcinoma of the thyroid; a clinicopathologic entity". J. Clin. Endocrinol. Metab. 19 (1): 152–61. doi:10.1210/jcem-19-1-152. PMID 13620740.
- ↑ Dionigi G, Bianchi V, Rovera F, et al. (2007). "Medullary thyroid carcinoma: surgical treatment advances". Expert Rev Anticancer Ther. 7 (6): 877–85. doi:10.1586/14737140.7.6.877. PMID 17555398.