Sandbox: Bone DDx
- 30-50 yo patients
- Unerupted teeth
- Oral ulcers
- Painless mandibular mass
- Lower jaw crepitus on palpation
- Facial deformity
- Multilocualted, expansile "soap-bubble" lesion, with well demarcated borders on X ray
- Mixed solid and cystic pattern on MRI
- Thick irregular wall, often with papillary solid structures projecting into the lesion on MRI
- Tall columnar cells with a palisaded nuclei and reverse polarization
- Subnuclear vacuolization
- Giant cells
- Subepithelial hyalinization
- BRAF V600E mutations