Intracerebral metastases (patient information)
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Overview
A metastatic brain tumor is cancer that started in another part of the body and spread to the brain.
What are the symptoms of Intracerebral metastases?
Symptoms may include any of the following:
Decreased coordination, clumsiness, falls Fever (sometimes) General ill feeling or lethargy Headache -- new or more severe than usual Memory loss, poor judgment, difficulty solving problems Numbness, tingling, pain, and other changes in sensation Personality changes Rapid emotional changes or strange behaviors Seizures that are new Speech difficulties Vision changes -- double vision, decreased vision Vomiting -- with or without nausea Weakness of a body area
Specific symptoms vary. The symptoms commonly seen with most types of metastatic brain tumor are those caused by increased pressure in the brain.
What causes Intracerebral metastases?
Many tumor or cancer types can spread to the brain. The most common are:
Bladder cancer Breast cancer Certain sarcomas Germ cell tumors Kidney cancer Leukemia Lung cancer Lymphoma Melanoma
Some types of cancer rarely spread to the brain, such as colon cancer and prostate cancer. In other rare cases, a tumor can spread to the brain from an unknown location. This is called cancer of unknown primary (CUP) origin.
Growing brain tumors can place pressure on nearby parts of the brain. Brain swelling due to these tumors also causes increased pressure within the skull.
Brain tumors that spread are classified based on the location of the tumor in the brain, the type of tissue involved, the original location of the tumor, and other factors. In rare cases, doctors do not know the original location. This is called cancer of unknown primary (CUP) origin.
Metastatic brain tumors occur in about one-fourth (25%) of all cancers that spread through the body. They are much more common than primary brain tumors (tumors that start in the brain).
Who is at highest risk?
Diagnosis
A neurologic examination can show brain and nervous system changes based on where the tumor is in the brain. Signs of increased pressure in the skull are also common. Some tumors may not show signs until they are very large. Then, they can cause a very quick decline in nervous system function.
The original (primary) tumor may be found by examining tumor tissues from the brain.
Tests may include:
Cerebral angiography Chest x-ray; mammogram; CT scans of the chest, abdomen, and pelvis to find the original tumor site CT scan or MRI of the brain to confirm the diagnosis and identify the tumor location (MRI is usually more sensitive for finding tumors in the brain) EEG Examination of tissue removed from the tumor during surgery or CT scan-guided biopsyto confirm the type of tumor Lumbar puncture (spinal tap)