Myelodysplastic syndrome causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
The cause of primary myelodysplastic syndrome has not been identified.[1] Common causes of secondary myelodysplastic syndrome include radiation, busulfan, nitrosourea, procarbazine, DNA topoisomerase inhibitors, acquired aplastic anemia, and Fanconi's anemia .[1]
Causes
Primary Myelodysplastic syndrome
Approximately 90% of MDS cases occur de novo with no identifiable cause.[1]
Secondary Myelodysplastic syndrome
Common causes of secondary myelodysplastic syndrome include:[1]
- Radiation
- Benzene
- Busulfan
- Nitrosourea
- Procarbazine
- DNA topoisomerase inhibitors
- Acquired aplastic anemia
- Fanconi's anemia
References
- ↑ 1.0 1.1 1.2 1.3 Risk factors of myelodysplastic syndrome. National Cancer Institute (2015). http://www.cancer.gov/types/myeloproliferative/hp/myelodysplastic-treatment-pdq/#link/_204_toc. Accessed on December 9, 2015