Splenic marginal zone lymphoma differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Overview

Splenic marginal zone lymphoma must be differentiated from other diseases such as chronic lymphocytic leukemia, follicular lymphoma, and mantle cell lymphoma.


Differential Diagnosis	CD5	CD10	Cyclin-D1

Splenic marginal zone lymphoma	Negative	Negative	Negative
Chronic lymphocytic leukemia	Positive	Negative	Negative
Follicular lymphoma	Negative	Positive	Positive
Mantle cell lymphoma	Positive	Negative	Positive

Splenic marginal zone lymphoma must be differentiated from other diseases such as: