MALT lymphoma medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Medical therapy
The various treatment options for MALT lymphoma include:
Treatment of MALT lymphoma | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Early stage (localized) | Advanced stage | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Pilomyxoid astrocytoma | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
WHO grade I | WHO grade II | WHO grade I | WHO grade II | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
If the disease is limited to the stomach (which is assessed with computed tomography), then 70-80% of patients will have a complete regression on treatment with antibiotic eradication of H. pylori. [1]
Radiotherapy
Others may be effectively controlled with the use of radiotherapy, or surgery. Both modalities may be curative in localized disease.
Chemotherapy
In contrast, if the disease has spread or has been refractory on antibiotics, chemotherapy may need to be considered.
References
- ↑ Bayerdörffer E, Neubauer A, Rudolph B, Thiede C, Lehn N, Eidt S, Stolte M (1995). "Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection. MALT Lymphoma Study Group". Lancet. 345 (8965): 1591–4. PMID 7783535.