Langerhans cell histiocytosis differential diagnosis
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Differentiating Langerhans cell histiocytosis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Langerhans cell histiocytosis must be differentiated from other diseases that cause bone pain, cutaneous lesions, hepatosplenomegaly, and palpable lymph nodes, such as cat-scratch disease, mastocytosis, sinus histiocytosis with massive lymphadenopathy.
Differentiating Langerhans cell histiocytosis from other Diseases
- Langerhans cell histiocytosis must be differentiated from other diseases that cause bone pain, cutaneous lesions, hepatosplenomegaly, and palpable lymph nodes, such as:
- Lymphoma
- Mastocytosis
- Cat-scratch disease
- Hypersensitivity reaction
- Acrodermatitis enteropathica
- Erdheim-Chester disease
- Wiskott-Aldrich syndrome
- Seborrheic dermatitis
- Sinus histiocytosis with massive lymphadenopathy
- Kimura disease
- Eosinophilic pustular folliculitis
- Erythema toxicum neonatorum
- Acropustulosis of infancy