Extramammary Paget's disease history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Symptoms of extramammary Paget's disease include pruritus, vulvar pain, vulvar bleeding, and burning sensation.[1][2][3]
History
In any patient with chronic dermatitis of the vulva, groin, or perianal are, the possibility of extramammary Paget disease (EMPD) should be carefully considered. Patients with EMPD usually present with nonresolving eczematous lesions in the genitalia, groin, perineum, or perianal area.[4]
Symptoms
The disease is asymptomatic in 10% of patients. The average time interval from the onset of symptoms to diagnosis is two years.[2][3][1] Symptoms of extramammary Paget's disease include the following:[1][2][3]
- Pruritis
- Pruritus is the most common symptom, occurring in around approximately 70% of patients
- Vulvar pain
- Vulvar bleeding
- Burning sensation
References
- ↑ 1.0 1.1 1.2 Zollo, J.D.; Zeitouni, N.C. (2000). "The Roswell Park Cancer Institute experience with extramammary Paget's disease". British Journal of Dermatology. 142 (1): 59–65. doi:10.1046/j.1365-2133.2000.03242.x. ISSN 0007-0963.
- ↑ 2.0 2.1 2.2 Parker LP, Parker JR, Bodurka-Bevers D, Deavers M, Bevers MW, Shen-Gunther J; et al. (2000). "Paget's disease of the vulva: pathology, pattern of involvement, and prognosis". Gynecol Oncol. 77 (1): 183–9. doi:10.1006/gyno.2000.5741. PMID 10739709.
- ↑ 3.0 3.1 3.2 Tebes S, Cardosi R, Hoffman M (2002). "Paget's disease of the vulva". Am J Obstet Gynecol. 187 (2): 281–3, discussion 283-4. PMID 12193912.
- ↑ Bagby CM, MacLennan GT (2009). "Extramammary Paget's disease of the penis and scrotum". J Urol. 182 (6): 2908–9. doi:10.1016/j.juro.2009.09.027. PMID 19846157.