Primary central nervous system lymphoma risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Risk Factors

The most potent risk factor in the development of primary central nervous system lymphoma is a weakened or suppressed immune system in individuals who have:

• Acquired immunodeficiency syndrome (AIDS)

• The highest number of cases occur in individuals with AIDS.

• Received an organ transplant and are on immunosuppressants
• Inherited immunosuppressive disorder