Croup future or investigational therapies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.
Overview
Future or Investigational Therapies
Heliox
- Helium and oxygen combined into "heliox" breathing gas can be used to alleviate croup symptoms by reducing upper airway obstruction.[1]
- Upper airway resistance to gas flow is reduced to relieve respiratory distress.
- There is evidence that suggests heliox can be as effective as racemic epinephrine in relieving moderate to severe croup symptoms.[2]
- Studies have not yet consistently determined if heliox is effective in treating all forms of croup and further investigational randomized trials are being pursued.[1]
References
- ↑ 1.0 1.1 Moraa, Irene; Sturman, Nancy; McGuire, Treasure; van Driel, Mieke L; Moraa, Irene (2013). "Heliox for croup in children". doi:10.1002/14651858.CD006822.pub4.
- ↑ Weber, J. E.; Chudnofsky, C. R.; Younger, J. G.; Larkin, G. L.; Boczar, M.; Wilkerson, M. D.; Zuriekat, G. Y.; Nolan, B.; Eicke, D. M. (2001). "A Randomized Comparison of Helium-Oxygen Mixture (Heliox) and Racemic Epinephrine for the Treatment of Moderate to Severe Croup". PEDIATRICS. 107 (6): e96–e96. doi:10.1542/peds.107.6.e96. ISSN 0031-4005.