Seminoma differential diagnosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Differentiating Seminoma from other Diseases
The most common presentation of testicular seminoma is a painless testicular mass.[1] The main differential for testicular mass in young adults is non-seminomatous germ cell tumor (NGCT) which usually appear more heterogenous, often with cysts and calcification.[2] Lymphadenopathy of non-seminomatous germ cell tumor may enhance more heterogenously. Testicular lymphoma is the main differential diagnosis to consider when para-aortic lymphadenopathy is the presenting finding or in the setting of bilateral testicular lesions.[2]
Testicular seminoma must be differentiated from:[3][4]
| Differential diagnosis of testicular seminoma | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Unilateral testicular mass | Bilateral testicular mass | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Neoplastic | Non neoplastic | Neoplastic | Non neoplastic | ||||||||||||||||||||||||||||||||||||||||||||||||
| Non seminomatous germ cell tumor ❑Testicular teratoma
❑Testicular epidermoid
❑Choriocarcinoma
❑Embryonal cell carcinoma
❑Yolk sac tumor
❑Mixed germ cell tumor | ❑Testicular cyst ❑Tubular ectasia of rete testes ❑Focal orchitis ❑Focal intratesticular hemorrhage ❑Testicular torsion ❑Segmental testicular infarction ❑Intra testicular adrenal rest ❑Focal granulomatous disease: ❑Tuberculosis ❑Sarcoidosis ❑Polyorchidism ❑Intratesticular varicocele ❑Intratesticular arteriovenous malformation | ❑Acute lymphoblastic leukemia ❑Chronic lymphocytic leukemia ❑Non-Hodgkin's lymphoma ❑Metastases | ❑Intra testicular adrenal rests | ||||||||||||||||||||||||||||||||||||||||||||||||
References
- ↑ Clinical presentation of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016
- ↑ 2.0 2.1 Differential diagnosis of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016
- ↑ Unilateral testicular lesions. Dr Yuranga Weerakkody and Dr Vinod G Maller et al. Radiopaedia 2016. http://radiopaedia.org/articles/unilateral-testicular-lesions. Accessed on February 25, 2016
- ↑ Bilateral testicular lesions. Dr Matt A. Morgan and Dr Vinod G Maller et al. Radiopaedia 2016. http://radiopaedia.org/articles/bilateral-testicular-lesions. Accessed on February 25, 2016