Hemosiderosis causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Causes
- There are no established causes for IPH, but it is likely to be multifactorial. Some consider it to be an autoimmune condition. The evidence is backed by the fact that the disease responds to immunosuppressants.
- Other hypotheses for the pathophysiology of the condition include allergy, due to its frequent association with Cow's milk protein allergy, genetic, due to the rare finding of familial clustering (but without any identified genes yet), and environmental due to the now refuted claim of its association with the fungi Stachybotrys atra exposure, toxic insecticides (based on epidemiological studies in rural Greece), premature birth.