Pheochromocytoma MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]

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Overview

Head, neck, chest, and abdominal MRI may be helpful in the diagnosis of pheochromocytoma.

Key MRI Findings in Pheochromocytoma

Key MRI findings in pheochromocytoma are:[1][2]

  • T1 slightly hypointense to the remainder of the adrenal gland, if there is a necrosis and/or haemorrhage then the signal will be more heterogeneous.
  • T2 markedly hyperintense lightbulb sign, helpful in the diagnosis, areas of necrosis/haemorrhage/calcification will alter signal. other adrenal tumors isointense such as liver.
  • T1 C+ (Gd) heterogenous enhancement is prolonged, persisting for as long as 50 minute
  • Increased attenuation on nonenhanced CT (>20 Hounsfield units.
  • Variable mass size and vascularity and may be bilateral.
  • T2 weighted MRI of the head, neck, and chest, and abdomen can help localize the tumor.

Patient #1: Bladder pheochromocytoma


Patient #2: Abdominal pheochromocytoma

References

  1. Pheochromocytoma. Dr Matt A. Morgan and Dr Frank Gaillard Gold Supporter since June 24, 2015">. Radiopaedia.org 2015.Page http://radiopaedia.org/articles/pheochromocytoma-2
  2. Bravo EL (1994). "Evolving concepts in the pathophysiology, diagnosis, and treatment of pheochromocytoma". Endocr Rev. 15 (3): 356–68. doi:10.1210/edrv-15-3-356. PMID 8076587.


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