Hypercalcemia historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]
Overview
In 1932, L. I. Pugsley AND Hans Selye, described the histological changes in the bone due to parathyroid hormone action and calcium metabolism in rat experiments. In the same year, Iftakhar Jahan and Robert F. Pitts described effect of parathyroid hormone in decreasing calcium and magnesium excretion.
Historical Perspective
Discovery
- In 1909, William George MacCallum and Carl Voegtlin, demonstrated association between parathyroid gland, calcium, and tetany.[1]
- In 1932, L. I. Pugsley AND Hans Selye, described the histological changes in the bone due to parathyroid hormone action and calcium metabolism in rat experiments. [2]
- In the same year, Iftakhar Jahan and Robert F. Pitts described effect of parathyroid hormone in decreasing calcium and magnesium excretion.[3]
Landmark Events in the Development of Treatment Strategies
- In 1925, Felix Mandl, a viennese surgeon, was the first who performed parathyroidectomy to treat a patient suffering from osteitis fibrosa cystica.[4]
Famous Cases
- Garry Shandling, a famous comedian suffered from hyperparathyroidism.[5]
References
- ↑ Maccallum WG, Voegtlin C (1909). "ON THE RELATION OF TETANY TO THE PARATHYROID GLANDS AND TO CALCIUM METABOLISM". J. Exp. Med. 11 (1): 118–51. PMC 2124703. PMID 19867238.
- ↑ PUGSLEY, L. I.; SELYE, HANS (July 28, 1933). "THE HISTOLOGICAL CHANGES IN THE BONE RESPONSIBLE FOR THE ACTION OF PARATHYROID HORMONE ON THE CALCIUM METABOLISM OF THE RAT". The Journal of Physiology. 79 (1): 113–117.
- ↑ JAHAN I, PITTS RF (1948). "Effect of parathyroid on renal tubular reabsorption of phosphate and calcium". Am. J. Physiol. 155 (1): 42–9. PMID 18102666.
- ↑ Thompson, Scott M.; Thompson, Geoffrey B. (April 8, 2015). Felix Mandl. Surgical Endocrinopathies. p. 153-156. ISBN 978-3-319-13661-5.
- ↑ "Garry Shandling and the Disease You Didn't Know About - The Atlantic".