Gonorrhea other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mehrsefat, M.D. [2]
Overview
Other diagnostic studies are used when NAAT or culture are not available. Other diagnostic studies for gonorrhea infection include rapid NAAT assay (modular-cartridge based platform), leukocyte esterase urine test, Immunochromatographic tests, Nucleic acid hybridization tests and enzyme immunoassay (EIA).[1][2][3]
Other diagnostic studies
Other diagnostic studies are used when NAAT or culture are not available.
Other diagnostic studies for gonorrhea infection include:[1][2][3]
- Rapid PCR test (modular-cartridge based platform)
- Detects nucleic acid of Chlamydia trachomatis and Neisseria gonorrhea in less than 2 hours (expensive)
- Leukocyte esterase urine dipsticks test
- Detects an enzyme found in certain white blood cells (WBC)
- Immunochromatographic tests
- Nucleic acid hybridization tests
- DNA probes labeled with a chemiluminescent marker is used to identify a specific nucleic acid sequence of the organism (less sensitive than NAAT)
- Enzyme immunoassay (EIA)
- Detects gonococcal antigens from cervical swab or urine specimens
References
- ↑ 1.0 1.1 Gaydos CA, Van Der Pol B, Jett-Goheen M, Barnes M, Quinn N, Clark C; et al. (2013). "Performance of the Cepheid CT/NG Xpert Rapid PCR Test for Detection of Chlamydia trachomatis and Neisseria gonorrhoeae". J Clin Microbiol. 51 (6): 1666–72. doi:10.1128/JCM.03461-12. PMC 3716060. PMID 23467600.
- ↑ 2.0 2.1 Watchirs Smith LA, Hillman R, Ward J, Whiley DM, Causer L, Skov S; et al. (2013). "Point-of-care tests for the diagnosis of Neisseria gonorrhoeae infection: a systematic review of operational and performance characteristics". Sex Transm Infect. 89 (4): 320–6. doi:10.1136/sextrans-2012-050656. PMID 23093736.
- ↑ 3.0 3.1 Vlaspolder F, Mutsaers JA, Blog F, Notowicz A (1993). "Value of a DNA probe assay (Gen-Probe) compared with that of culture for diagnosis of gonococcal infection". J Clin Microbiol. 31 (1): 107–10. PMC 262630. PMID 8417014.