Churg-Strauss syndrome history and symptoms
|
Churg-Strauss syndrome Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Churg-Strauss syndrome history and symptoms On the Web |
|
American Roentgen Ray Society Images of Churg-Strauss syndrome history and symptoms |
|
Risk calculators and risk factors for Churg-Strauss syndrome history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3]
Overview
History
Obtaining a complete history is an important aspect in making a clinical diagnosis of Eosinophilic granulomatosis with polynagiitis. As it can help differentiate between the ANCA associated vasculitis and other possible causes that may mimic the disease. They include:
- Granulomatosis with polyangiitis
- Microscopic polyangiitis
- Idiopathic hyper-eosinophilic syndrome
- Drug induced
Symptoms
The initial signs that are seen in patients presenting with Eosinophilic granulomatosis with polyangiitis are non-specific in nature. The following are signs and symptoms of Eosinophilic granulomatosis with polyangiitis:[1]
Prodromal phase
- Arthralgia
- Myalgia
- Pyrexia
- Weight loss
- Asthma
- Nasal polyps
- Allergic rhinitis,
- Sinusitis
- Otitis media
- Sensorineural hearing loss
- Asthenia
Eosinophilic phase
- Peripheral eosinophilia
- Pulmonary infiltrates
- Ground glass opacities
- Thickening of the bronchial wall
- Endomyocardial infiltrates
- Arrhythmia
- Pericarditis
- Abdominal pain
Vascular phase
- Pyrexia
- Weight loss
- Fatigue
- Multiplex mononeuritis
- Cerebral infarctions
- Rapid progressive glomerulonephritis
- Pauci-immune focal and segmental necrotizing glomerulonephritis
- Palpable purpura and nodules
- Maculopapular erythematous
- Livedo reticularis
- Petechiae
- Ecchymoses
References
- ↑ Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Ruoppolo G; et al. (2015). "Churg-Strauss syndrome". Autoimmun Rev. 14 (4): 341–8. doi:10.1016/j.autrev.2014.12.004. PMID 25500434.