Approaches to Glycemic Treatment in Diabetes
2016 ADA Guideline Recommendations |
Types of Diabetes Mellitus |
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2016 ADA Standard of Medical Care Guideline Recommendations |
Cardiovascular Disease and Risk Management |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shivani Chaparala M.B.B.S [2]; Tarek Nafee, M.D. [3]
2016 ADA Standards of Medical Care in Diabetes Guidelines
PHARMACOLOGICAL THERAPY FOR TYPE 1 DIABETES
"1. Most people with type 1 diabetes should be treated with multiple-dose insulin injections (three to four injections per day of basal and prandial insulin) or continuous subcutaneous insulin infusion. (Level of Evidence: A)" |
"2. Consider educating individuals with type 1 diabetes on matching prandial insulin dose to carbohydrate intake, premeal blood glucose, and anticipated activity. (Level of Evidence: E)" |
"3. Most individuals with type 1 diabetes should use insulin analogs to reduce hypoglycemia risk. '(Level of Evidence: A)" |
"4. Individuals who have been successfully using continuous subcutaneous insulin
infusion should have continued access after they turn 65 years of age. (Level of Evidence: E)" |
PHARMACOLOGICAL THERAPY FOR TYPE 2 DIABETES
"1. Metformin, if not contraindicated and if tolerated, is the preferred initial pharmacological agent for type 2 diabetes. (Level of Evidence: A)" |
"2. Consider initiating insulin therapy (with or without additional agents) in patients with newly diagnosed type 2 diabetes and markedly symptomatic and/or elevated blood glucose levels or A1C. '(Level of Evidence: E)" |
"3. If noninsulin monotherapy at maximum tolerated dose does not achieve or maintain the A1C target over 3 months, then add a second oral agent, a glucagon-like peptide 1 receptor agonist, or basal insulin. '(Level of Evidence: A)" |
"4. A patient-centered approach should be used to guide the choice of pharmacological agents. Con- siderations include efficacy, cost, potential side effects, weight, co- morbidities, hypoglycemia risk, and patient preferences. (Level of Evidence: E)" |
"5. For patients with type 2 diabetes who are not achieving glycemic goals, insulin therapy should not be delayed. (Level of Evidence: B)" |